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About Donum Therapeutics

 Donum Therapeutics is currently a virtual company with the Executive Team and SAB are all very actively engaged as consultants.  Our overall business plan is to create a product engine that develops in-licensed lead- quality antibacterial compounds with activity against resistant pathogens, suitable PK, and in vivo activity in from Lewis’ lab and elsewhere through lead optimization, pre-clinical candidate selection and possibly into the clinic.

Our Founding Team

David Pompliano, PhD.

 CEO, Co-Founder ,  Director of Donum Therapeutics 


 Extensive experience in the discovery and development of anti-infective and oncology drugs within both large pharmaceutical companies and small biotechnology firms 

  

Co-founder and CSO/CEO of Revolution Medicines (RVMD), Lodo Therapeutics , Daros, Odyssey Therapeutics


·Former Entrepreneur in Residence at Third Rock Ventures


Former VP, Global Basic Head, Infectious Diseases Franchise at Merck; 

·Former VP, Head of Biology for MMPD and Infectious Diseases CEDDs at GSK

Advisory boards for ENABLE, Gates Foundation TB Drug Accelerator,  Broad Institute, various NIAID- initiatives and biotech companies


BS Chemistry, UVA; PhD Chemistry, Stanford; Post-doc, Harvard (Jeremy Knowles)

  

 https://www.linkedin.com/in/davidpompliano

Kim Lewis, PhD.

 Co-Founder, Director of Donum Therapeutics 

  

Professor of Biology; Director, Antimicrobial Discovery Center; Northeastern University


Expert in microbial drug resistance and drug discovery


PhD, Biochemistry, Moscow University


Previously faculty of MIT, University of Maryland, and Tufts University


Fellow of American Academy of Microbiology and of American Association for the Advancement of Science


Inventor in  the discovery and characterization of darobactin 


 https://www.linkedin.com/in/kim-lewis-b429b819

Phil Baran, Phd.

Co-Founder 


Professor of Chemistry, Scripps Research Institute; Dr. Richard A. Lerner Endowed Chair 


Expert in organic synthesis


BS, New York University, PhD, Scripps Research; Post-doc, Harvard University

Danisco Foundation Science Excellence Award, the Manchot Research Professorship Award, the Emanuel Merck Lectureship, the ACS Elias J. Corey Award, the Blavatnik National Laureate in Chemistry Award and a MacArthur Fellowship


Member National Academy of Sciences, American Academy of Arts and Sciences; Fellow of the Royal Society of Chemistry


 https://www.scripps.edu/faculty/baran

Scientific Advisory Board

 Our Scientific Advisory Board is a mix of  well-respected experts in antibacterial drug discovery from both the pharmaceutical industry and academia.


Phil Baran, PhD (medchem) and Kim Lewis, PhD (antibiotic discovery)


Sebastian Hiller, PhD (computational chemistry and structural biology); Professor at the Biozentrum of the University of Basel, Switzerland;  ICMRBS Founder’s Medal;  EMBO Young Investigator. https://www.biozentrum.unibas.ch/research/research-groups/research-groups-a-z/own-content/unit/research-group-sebastian-hiller/hiller-cv 


Carole Sable, MD (infectious disease physician) Former VP, Infectious Disease franchise at Merck; Former CMO at Novexel, Scynexis, and Arixa. Advisor to Novo REPAIR Fund and GARDP. https://www.linkedin.com/in/carole-sable/


Ruben Tommasi, PhD (medchem), CSO Dunad, former CSO Entasis, former Head, Infection Chemistry, AstraZeneca.  https://www.linkedin.com/in/ruben-tommasi/


Jennifer Leeds, PhD (drug discovery, business development) Head, West Coast Business Development, Novartis; former head of Antibacterial Discovery, Novartis.  https://www.linkedin.com/in/jaleeds/


Terry Roemer, PhD (discovery microbiology), CEO, Prokaryotics; former head of Antibacterial Discovery, Merck.   https://www.linkedin.com/in/terry-roemer-4b1a39149/

Collaborators and Consultants

 Sebastian Hiller, PhD (computational chemistry and structural biology).


Joseph Vacca PhD (medicinal chemistry), Owner J. Vacca Consulting LLC, former Executive Director, Chemistry, Merck,  Merck Directors Award; PhRMA Discoverers Award; Intellectual Property Owners "National Inventor of the year Award", European Inventor of the Year,  American Chemical Society Medicinal Chemistry Hall of Fame.


Patricia Bradford, PhD (owner Antimicrobial Development Specialists LLC), formerly Executive Director, Head of Development Microbiology for Infectious Disease Research, Astra Zeneca.


Michael Pucci, PhD (antimicrobial consultant Antimicrobial Development Specialists LLC), formerly Executive Director at Sphero  and Achillion. 


Kim Lewis Lab and Antibiotic Discovery Center,  https://lewislab.sites.northeastern.edu/

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